CENPE Monoclonal Antibody [1H12] - Unconjugated / 0.1ml IQ201 from ImmuQuest Ltd.

Product Specs
ItemCENPE Monoclonal Antibody [1H12] - Unconjugated / 0.1ml
CompanyImmuQuest Ltd.
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberIQ201
ImmunogenRecombinant full length CENPE protein (human)
PurityAffinity purified by ion exchange chromatography
HostMouse
Quantity0.1mg
ReactivityHuman
IsotypeIgG1 kappa
ApplicationsICC/IF, IP, ICC, Flow Cyt
Clone1H12
FormatPurified antibody (from supernatant) containing PBS 0.1% sodium azide;
Concentration1mg/ml
Research AreaCentromere; Chromatin;
NCBI Full Gene Namecentromere protein E
NCBI Gene AliasesCENP-E, KIF10, MCPH13, PPP1R61
ClonalityMonoclonal
Conjugate/TagUnconjugated
TargetCENPE

Specifications/Features

Myeloma/fusion partners: SP2/0

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ImmuQuest Ltd.

Springboard Business Centre

Ellerbeck Way Stokesley Business Park

N.Yorkshire TS9 5JZ

United Kingdom

Company Profile

Website: http://www.immuquest.com

(1) LUBAC controls chromosome alignment by targeting CENP-E to attached kinetochoresNature communicationsJanuary 17, 2019Wu M, Chang Y, Hu H, Mu R, Zhang Y, Qin X, Duan X, Li W, Tu H, Zhang W, et al.

(2) Environmental stresses induce karyotypic instability in colorectal cancer cellsMolecular biology of the cellJanuary 1, 2019Tan Z, Chan YJA, Chua YJK, Rutledge SD, Pavelka N, Cimini D, Rancati G.

(3) Distinct Roles of RZZ and Bub1-KNL1 in Mitotic Checkpoint Signaling and Kinetochore ExpansionCurrent biology : CBNovember 5, 2018Rodriguez-Rodriguez JA, Lewis C, McKinley KL, Sikirzhytski V, Corona J, Maciejowski J, Khodjakov A, Cheeseman IM, Jallepalli PV.

(4) Self-Assembly of the RZZ Complex into Filaments Drives Kinetochore Expansion in the Absence of Microtubule AttachmentCurrent biology : CBNovember 5, 2018Pereira C, Reis RM, Gama JB, Celestino R, Cheerambathur DK, Carvalho AX, Gassmann R.

(5) Microtubules assemble near most kinetochores during early prometaphase in human cellsThe Journal of cell biologyAugust 6, 2018Sikirzhytski V, Renda F, Tikhonenko I, Magidson V, McEwen BF, Khodjakov A.

(6) Non-random Mis-segregation of Human ChromosomesCell reportsJune 12, 2018Worrall JT, Tamura N, Mazzagatti A, Shaikh N, van Lingen T, Bakker B, Spierings DCJ, Vladimirou E, Foijer F, McClelland SE.

(7) Antagonism between the dynein and Ndc80 complexes at kinetochores controls the stability of kinetochore-microtubule attachments during mitosisThe Journal of biological chemistryApril 20, 2018Amin MA, McKenney RJ, Varma D.

(8) Aurora B prevents premature removal of spindle assembly checkpoint proteins from the kinetochore: A key role for Aurora B in mitosisOncotargetApril 13, 2018Gurden MD, Anderhub SJ, Faisal A, Linardopoulos S.

(9) Interplay between the phosphatase PHLPP1 and E3 ligase RNF41 stimulates proper kinetochore assembly via the outer-kinetochore protein SGT1The Journal of biological chemistryAugust 25, 2017Gangula NR, Maddika S.

(10) Midbody assembly and its regulation during cytokinesisMolecular biology of the cellMarch 1, 2012Hu CK, Coughlin M, Mitchison TJ.

(11) Small GTPase Rab5 participates in chromosome congression and regulates localization of the centromere-associated protein CENP-F to kinetochoresProceedings of the National Academy of Sciences of the United States of AmericaOctober 18, 2011Serio G, Margaria V, Jensen S, Oldani A, Bartek J, Bussolino F, Lanzetti L.

(12) Telomere disruption results in non-random formation of de novo dicentric chromosomes involving acrocentric human chromosomesPLoS geneticsAugust 12, 2010Stimpson KM, Song IY, Jauch A, Holtgreve-Grez H, Hayden KE, Bridger JM, Sullivan BA.

(13) Aurora kinases and protein phosphatase 1 mediate chromosome congression through regulation of CENP-ECellAugust 6, 2010Kim Y, Holland AJ, Lan W, Cleveland DW.

(14) Mediator of DNA damage checkpoint 1 (MDC1) regulates mitotic progressionThe Journal of biological chemistryDecember 4, 2009Townsend K, Mason H, Blackford AN, Miller ES, Chapman JR, Sedgwick GG, Barone G, Turnell AS, Stewart GS.

(15) Glycogen synthase kinase 3beta interacts with and phosphorylates the spindle-associated protein astrinThe Journal of biological chemistryJanuary 25, 2008Cheng TS, Hsiao YL, Lin CC, Yu CT, Hsu CM, Chang MS, Lee CI, Huang CY, Howng SL, Hong YR.

(16) Farnesyl transferase inhibitors impair chromosomal maintenance in cell lines and human tumors by compromising CENP-E and CENP-F functionMolecular cancer therapeuticsApril 1, 2007Schafer-Hales K, Iaconelli J, Snyder JP, Prussia A, Nettles JH, El-Naggar A, Khuri FR, Giannakakou P, Marcus AI.

(17) PIASgamma is required for faithful chromosome segregation in human cellsPloS oneDecember 20, 2006Díaz-Martínez LA, Giménez-Abián JF, Azuma Y, Guacci V, Giménez-Martín G, Lanier LM, Clarke DJ.

(18) Tankyrase-1 polymerization of poly(ADP-ribose) is required for spindle structure and functionNature cell biologyNovember 1, 2005Chang P, Coughlin M, Mitchison TJ.

(19) CENP-E, a novel human centromere-associated protein required for progression from metaphase to anaphaseThe EMBO journalMay 1, 1991Yen TJ, Compton DA, Wise D, Zinkowski RP, Brinkley BR, Earnshaw WC, Cleveland DW.

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CENPE Antibody [1H12]

CENPE Monoclonal Antibody [1H12] - Unconjugated / 0.1ml from ImmuQuest Ltd.

Specifications/Features

ImmuQuest Ltd.

Citations (19)

Reviews

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Webinar: Improving Cancer Biomarker Detection with Multiplex Technology

Screening of Leukemic Neoantigen Specific T cells with the iQue Screener PLUS

CENPE Monoclonal Antibody [1H12] - Unconjugated / 0.1ml from ImmuQuest Ltd.

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